Still Too Few Women in Stroke Treatment Clinical Trials

Researchers say men outnumber women in stroke therapy clinical trials, which means women may end up receiving less effective treatment.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Conclusions An intensive course of tDCS, as delivered in this study, does not improve motor, mood, and cognitive outcomes in ischemic/hemorrhagic stroke in patients undergoing individualized rehabilitation. The study provides important leads for directions for future research.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Condition:   Stroke Interventions:   Device: Soft exosuit;   Behavioral: No Soft exosuit Sponsors:   Boston University Charles River Campus;   American Heart Association;   Harvard University;   Spaulding Rehabilitation Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Samsung NeuroLogica has released its multislice, small-bore, mobile OmniTo...Read more on AuntMinnie.comRelated Reading: Samsung NeuroLogica nets FDA clearance for AI tool Samsung NeuroLogica gets nod for ultrasound sales to U.S. military NeuroLogica launches new mobile stroke CT scanner NeuroLogica boosts CT manufacturing for virus scanning Samsung NeuroLogica lands Memorial Sloan Kettering
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
a Turolla Recent studies have investigated muscle synergies as biomarkers for stroke, but it remains controversial if muscle synergies and clinical observation convey the same information on motor impairment. We aim to identify whether muscle synergies and clinical scales convey the same information or not. Post-stroke patients were administered an upper limb treatment. Before (T0) and after (T1) treatment, we assessed motor performance with clinical scales and motor output with EMG-derived muscle synergies. We implemented an exploratory factor analysis (EFA) and a confirmatory factor analysis (CFA) to identify the und...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
Conclusion: This Bayesian network meta-analysis results show that the combination of qualified TCMIs and CT is more effective for HFrEF patients than CT alone, and CT + XML and CT + SM may be one of the potential optimal treatments. Also, the safety of these TCMIs needs to be further observed. However, due to some limitations, the conclusions need to be verified by more large-sample, double-blind, multi-center RCTs.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed when certain areas of cerebral infarction appear as cerebral hemorrhage on radiological images. Its mechanisms are usually explained by disruption of the blood-brain barrier and reperfusion injury that causes leakage of peripheral blood cells. In ischemic infarction, HT may be a natural progression of acute ischemic stroke and can be facilitated or enhanced by reperfusion therapy. Therefore, to balance risks and benefits, HT occurrence in ac...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions: Four stages of CSVD severity in SHRSP are described at the study time points. In addition, we find that quantitative analyses of brain MRI enable identification of in vivo markers of CSVD that can serve as endpoints for interventional testing in therapeutic studies.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: We describe severe behavioral problems after hemispherotomy that subsided when valproate was tapered off. While we cannot rule out a spontaneous correction of a post-hemispherotomy network dysregulation, our report raises awareness to possible altered effects of the anticonvulsant valproic acid parallel to reorganizational processes after hemispherotomy.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In most patients with intracerebral hemorrhage (ICH), the hematoma and perihematomal area decrease over the subsequent months but patients continue to exhibit neurological impairments. In this serial imaging study, we characterized microstructural and neurophysiological changes in the ICH-affected brain tissues and collected the National Institute of Health Stroke Scale (NIHSS) and modified Rankin Score (mRS), two clinical stroke scale scores. Twelve ICH patients were serially imaged on a 3T MRI at 1, 3, and 12 months (M) after injury. The hematoma and perihematomal volume masks were created and segmented using FLAIR imagi...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion: Over 12 weeks, the combination of balance training with VNF and Ginkgo biloba dry extract EGb 761 reached a clinically relevant improvement of age-related vertigo and dizziness with a good pharmacological safety profile.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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