Prostate zones and cancer: lost in transition?

Nature Reviews Urology, Published online: 19 October 2021; doi:10.1038/s41585-021-00524-7The prostate is divided into the peripheral, transition and central zones, which have different prostate cancer incidences and prognoses. Differences between the zones suggest their potential roles in tumour aggressiveness, but treatment of prostate cancer remains zonal agnostic. Improved understanding of the zones and their roles in tumorigenesis could improve prostate cancer management.

Source: Nature Reviews Urology - October 19, 2021 Category: Urology & Nephrology Authors: Amin Ali Alexander Du Feu Pedro Oliveira Ananya Choudhury Robert G. Bristow Esther Baena Source Type: research