Optimization of sepsis therapy based on patient-specific digital precision diagnostics using next generation sequencing (DigiSep-Trial) —study protocol for a randomized, controlled, interventional, open-label, multicenter trial

DiscussionThe authors ´ previous work suggests that NGS-based diagnostics have a higher specificity and sensitivity compared to standard-of-care microbiological analyses for detecting bloodstream infections. In combination with the here presentedDigiSep-Trial, this work provides the optimal basis to establish a new NGS-driven concept as part of the national standard based on the best possible evidence.Trial registrationsDRKS-IDDRKS00022782. Registered on August 25, 2020ClinicalTrials.govNCT04571801. Registered October 1, 2020
Source: Trials - Category: Research Source Type: clinical trials