sciCNV: high-throughput paired profiling of transcriptomes and DNA copy number variations at single-cell resolution

In conclusion, we provide new tools for scRNA-seq that enable paired profiling of the CNVs and transcriptomes of single cells, facilitating rapid and accurate deconstruction of the effects of cancer CNVs on cellular programming.PMID:34655292 | DOI:10.1093/bib/bbab413

Source: Briefings in Bioinformatics - October 16, 2021 Category: Bioinformatics Authors: Ali Mahdipour-Shirayeh Natalie Erdmann Chungyee Leung-Hagesteijn Rodger E Tiedemann Source Type: research