FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1 β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway

In conclusion, FABP4 knockdown suppressed the inflammation, oxidative stress, apoptosis and extracellular matrix degradation of IL‑1β‑induced chondrocytes by activating PPARγ to inhibit the NF‑κB signaling pathway.PMID:34651666 | DOI:10.3892/mmr.2021.12495

Source: Molecular Medicine - October 15, 2021 Category: Molecular Biology Authors: Huajie Mao Bin Han Hao Li Yiqing Tao Weigang Wu Source Type: research