Matrix metalloproteinase-9 inhibition or deletion attenuates portal hypertension in rodents

In conclusion, MMP-9 inhibition or deletion ameliorated the severity of cirrhosis, portal hypertension, and associated derangements. MMP-9 may be targeted in the treatment of liver cirrhosis.PMID:34647412 | DOI:10.1111/jcmm.16940

Source: J Cell Mol Med - October 14, 2021 Category: Molecular Biology Authors: Hui-Chun Huang Hsin-Ling Ho Ching-Chih Chang Chiao-Lin Chuang Chon Kit Pun Fa-Yauh Lee Yi-Hsiang Huang Ming-Chih Hou Shao-Jung Hsu Source Type: research