Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies

ConclusionNo survival advantage for the general use of chemotherapy in recurrent EPN was found. In cases with incomplete resection, chemotherapy was able to extend survival in individual cases. Sirolimus showed the best RR, DOR and TTP out of all drugs analyzed and may warrant further investigation.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research