A copper(I)-catalyzed sulfonylative Hiyama cross-coupling

Chemistry. 2021 Oct 15. doi: 10.1002/chem.202103371. Online ahead of print.ABSTRACTAn air-tolerant Cu-catalyzed sulfonylative Hiyama crosscoupling reaction enabling the formation of diaryl sulfones is described. Starting from aryl silanes, DABSO and aryliodides, the reaction tolerates a large variety of polar functional groups (amines, ketones, esters, aldehydes). Control experiments coupled with DFT calculations shed light on the mechanism, characterized by the formation of a Cu(I)-sulfinate intermediate via fast insertion of a SO 2 molecule.PMID:34652867 | DOI:10.1002/chem.202103371

Source: Chemistry - October 15, 2021 Category: Chemistry Authors: Aur élien Adenot Lucile Anthore-Dalion Emmanuel Nicolas Jean-Claude Berthet Pierre Thu éry Thibault Cantat Source Type: research