Accumbal Histamine Signaling Engages Discrete Interneuron Microcircuits
Central histamine (HA) signaling modulates diverse cortical and subcortical circuits throughout the brain, including the nucleus accumbens (NAc). The NAc, a key striatal subregion directing reward-related behavior, expresses diverse HA receptor subtypes that elicit cellular and synaptic plasticity. However, the neuromodulatory capacity of HA within interneuron microcircuits in the NAc remains unknown.
Source: Biological Psychiatry - Category: Psychiatry Authors: Kevin M. Manz, Lillian J. Brady, Erin.S. Calipari, Brad A. Grueter Tags: Archival Report Source Type: research