Factors behind the prevalence of carbapenem-resistant Klebsiella pneumoniae in pediatric wards.

The emergence of carbapenem-resistant Enterobacteriaceae made the treatment difficult, which has become a significant issue of public health. A sharp increase of carbapenem-resistance rate in Klebsiella pneumoniae was observed in a maternity and child health care hospital in Zunyi, China, in 2014.In 2015 to 2016, carbapenem-resistant Klebsiella pneumoniae (CRKp) isolated from all the clinical samples were analyzed to identify the carbapenem-resistance genes. They were then fingerprinted in order to determine their genetic relationship. Clinical data such as usage of imipenem in 2012 to 2016 and the nosocomial infection surveillance data were analyzed. Thirty-five isolates of CRKp out of 4328 various pathogens were obtained, and blaNDM-1 was identified to be the most common resistant gene present in the CRKp isolates. The fingerprint analysis identified 15 major clusters of CRKp isolates. The bacteria with close proximity relationship tended to be from the same wards. However, a few CRKp isolates from different wards were found to be genetically highly related. The clinical data showed a significantly higher usage of carbapenems in 2012 to 2013 before the CRKp rate sharply increased in 2014. The nosocomial infection surveillance showed an unexpectedly high rate of failures to meet the requirement of the hospital environment hygiene and hand hygiene in the neonatal ward.The increasing isolation rate of CRKp was associated with poorly regulated usage of carbapenems, impropriate ...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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In this issue of Heart, Lung and Circulation, Chong et  al. [1] review and summarise the current management and outcomes of proximal aortic graft infection (PAGI). Their systematic review included 20 studies representing 290 PAGI patients who underwent reoperation or treatment with antibiotics alone (25 patients); they concluded that prompt referral to specialised aortic centres is recommended, to plan for best management strategies and improve patient outcomes [1]. This editorial aims to shed light on some critical aspects of managing this infrequent and challenging surgical problem, and to discuss the complexities o...
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Editorial Source Type: research
Source: Heart, Lung and Circulation - Category: Cardiology Source Type: research
Source: Heart, Lung and Circulation - Category: Cardiology Source Type: research
Source: Heart, Lung and Circulation - Category: Cardiology Source Type: research
Dysfunctional breathing, hypocapnia, and myalgic encephalomyelitis/chronic fatigue syndrome were seen in symptomatic patients post-acute COVID-19 despite normal chest imaging and pulmonary function.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news
The expanded approval is for the adjuvant treatment of advanced melanoma after complete resection in patients aged 12 years and older.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Two days after the first case of the new Omicron Covid-19 variant was officially confirmed in Massachusetts, the head of the state's largest hospital system stressed the importance of vaccines and masks.
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Blind source separation algorithms such as independent component analysis (ICA) are widely used in the analysis of neuroimaging data. To leverage larger sample sizes, different data holders/sites may wish to collaboratively learn feature representations. However, such datasets are often privacy-sensitive, precluding centralized analyses that pool the data at one site. In this work, we propose a differentially private algorithm for performing ICA in a decentralized data setting. Due to the high dimension and small sample size, conventional approaches to decentralized differentially private algorithms suffer in terms of util...
Source: IEEE Transactions on Signal Processing - Category: Biomedical Engineering Source Type: research
When people listen to speech, neural activity tracks the entropy fluctuation in the acoustic envelope of the signal. This signal-based entrainment has been shown to be the basis of speech parsing and comprehension. In this electroencephalography (EEG) study, we compute sign language users’ cortical tracking of changes in visual dynamics of the communicative signal in the time-direct videos of sign language, and their time-reversed counterparts, and assess the relative contribution of response frequencies between.2 and 12.4 Hz to comprehension using a machine learning approach to brain state classification. Lower freq...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - Category: Neuroscience Source Type: research
This study aimed to explore the associated factors of stigma towards people with mental illness among Omani school and university students.Design and MethodA cross-sectional study among 371 school and university students with a multivariable linear regression model to identify the associated factors of personal and perceptions of stigma.ResultsMale students, those with highly educated mothers, have high monthly income, higher mental health knowledge, employed fathers, and received focused education on mental illness showed fewer stigmatizing attitudes.Implications for PracticeEnhancing the knowledge about mental illness am...
Source: Perspectives in Psychiatric Care - Category: Psychiatry Authors: Tags: ORIGINAL ARTICLE Source Type: research
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