Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors

CONCLUSIONS: In a side-by-side comparison, FGS with uPAR-targeting antibody fragments compared with the parent IgG resulted in earlier tumor visualization at the expense of peak fluorescence intensity.PMID:34642899 | DOI:10.1007/s11307-021-01657-2

Source: Mol Biol Cell - October 13, 2021 Category: Molecular Biology Authors: Victor M Baart Labrinus van Manen Shadhvi S Bhairosingh Floris A Vuijk Luisa Iamele Hugo de Jonge Claudia Scotti Massimo Resnati Robert A Cordfunke Peter J K Kuppen Andrew P Mazar Jacobus Burggraaf Alexander L Vahrmeijer Cornelis F M Sier Source Type: research