Cancers, Vol. 13, Pages 5168: Development of a MicroRNA Signature Predictive of Recurrence and Survival in Pancreatic Ductal Adenocarcinoma

Conclusions: RS predicted worse LRR and OS in R-PDAC and worse LRR, DR, and OS in BR/LA-PDAC. This may select patients who would benefit from radiation and should be validated prospectively.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research

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Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Source: Cancer Management and Research - Category: Cancer & Oncology Tags: Cancer Management and Research Source Type: research
Dalton Trans., 2021, Accepted Manuscript DOI: 10.1039/D1DT03364F, PaperDejan Simic, Milan Zaric, Ivana Nikolic, Radica Zivkovic Zaric, Petar Canovic, Aleksandar Kocovic, Ivana Radojevic, Ivana Rakovic, Sandra Jovicic Milic, Djordje Petrovic, Danijela Stojkovic, Nenad Vukovic, Miroslava Ka čániová, Milena Vukic, Verica Jevtic A five new complexes of palladium(II) ion (C1 –C5) general formula [PdL2)]Cl2 with some 2-aminothiazoles (L1-L5) whereL1 = 2-amino-4-(3,4 difluorophenyl) thiazole,L2 = 2-amino-5-methyl-4-phenylthiazole,L3 = 2-amino-4-phenylthiazole,L4 = 2-amino-4-(4-chlorophenyl)... The content of ...
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Chris EdwardsThe main weapons against COVID-19 are the vaccines developed by Moderna and BioNTech after a decade of their research into mRNA technologies. That research was supported by more than $3 billion of private angel investment and venture capital.Democrats and Republicans both support medical research funding, and Republicans tout the Trump administration ’s Operation Warp Speed. But governments were not the key to mRNA development. Instead, we can thank the leaders and scientists at Moderna and BioNTech and the suppliers of private capital to them, as I discusshere andhere.TheWall Street Journal &r...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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Source: Cancer Nursing - Category: Nursing Tags: DEPARTMENTS: Guest Editorial Source Type: research
Background Fatigue and sleep disturbance are common co-occurring symptoms in patients receiving chemotherapy. While the results from meta-analyses support the use of exercise to decrease the severity of these symptoms, information is needed on patients’ “real world experiences” with the use of exercise. Objective The aims of this study were to determine distribution of patients who did and did not exercise on a regular basis and evaluate for differences in demographic and clinical characteristics, as well as the severity of fatigue, decrements in energy, and sleep disturbance among the exercise...
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
Conclusion Diagnosis and treatment create an opportunity for the women to critically reflect on their lives and to develop new life perspectives. During treatment, a mental transformation involving the use of various individual social, mental, and physical coping strategies allowed the women to manage their daily lives. This enabled self-management strategies, resulting in maintaining a sense of normalcy, trying to defy the adverse effects, and prioritizing themselves, their families, and the treatment. Implications for Practice Women with cervical cancer undergoing oncological treatment need more specific and d...
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES Source Type: research
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with poor survival rates. For borderline resectable or unresectable disease, intensive multi ‐drug chemotherapy regimens with either modified FOLFIRINOX (mFOLF) or nab‐paclitaxel plus gemcitabine are preferred. We retrospectively compared these two chemotherapy regimens in patients who completed resection and found the mFOLF group had better overall clinical and pathological response ra tes. Randomized clinical trials are needed, and this study provides valuable information in the interim. AbstractWe conducted an institutional study to compare the clinical and...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Systemic immune activity predicts overall survival in treatment naïve patients with metastatic pancreatic cancer. Clin Cancer Res. 2015 Dec 30; Authors: Farren MR, Mace T, Geyer S, Mikhail S, Wu C, Ciombor KK, Tahiri S, Ahn D, Noonan AM, Villalona-Calero MA, Bekaii-Saab T, Lesinski GB Abstract BACKGROUND &AIMS: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a 5-year survival rate
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
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