Cadmium hijacks the high zinc response by binding and activating the HIZR-1 nuclear receptor [Genetics]

Cadmium is an environmental pollutant and significant health hazard that is similar to the physiological metal zinc. In Caenorhabditis elegans, high zinc homeostasis is regulated by the high zinc activated nuclear receptor (HIZR-1) transcription factor. To define relationships between the responses to high zinc and cadmium, we analyzed transcription. Many...

Source: Proceedings of the National Academy of Sciences - October 14, 2021 Category: Science Authors: Brian J. Earley, Ciro Cubillas, Kurt Warnhoff, Raheel Ahmad, Alan Alcantar, Maximilian D. Lyon, Daniel L. Schneider, Kerry Kornfeld Tags: Genetics Biological Sciences Source Type: research