The association between coffee consumption and periodontitis: a cross-sectional study of a northern German population Julia Struppek, Carolin Walther, K übra Bunte, Birgit-Christiane Zyriax, Jan-Per Wenzel, Juliana Senftinger, Julius Nikorowitsch, Guido Heydecke, Udo Seedorf, Thomas Beikler, Katrin Borof,

Conclusionand clinical relevance.In this cross-sectional study of a northern German population, strong coffee consumption was significantly associated with periodontitis. Influence of changes in coffee consumption on periodontal disease etiology/progression should be investigated in future prospective study designs, in order to identify strong coffee consumption as a potential risk factor of periodontitis.
Source: Dental Technology Blog - Category: Dentistry Source Type: news

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Background Elderly constitute a high-risk subset of patients but are under-represented in clinical revascularization trials. Our aim was to investigate clinical outcomes and prognosis predictors after percutaneous coronary intervention (PCI) in this population. Methods Unrestricted consecutive patients with ≥75 years who underwent PCI from 2012 to 2015 were enrolled. The primary ischemic endpoint was the composite of 1-year myocardial infarction, definite/probable stent thrombosis and target vessel revascularization. The primary bleeding endpoint was defined according to the Bleeding Academic Research Consort...
Source: Coronary Artery Disease - Category: Cardiology Tags: PCI Source Type: research
Since the emergence of the COVID-19 pandemic, Johnson &Johnson (the Company) has been closely monitoring newly emerging COVID-19 variants. In collaboration with academic groups in South Africa and around the world, the Company has been evaluating the effectiveness of its COVID-19 vaccine across variants, including now the new and rapidly spreading Omicron variant. The Company is testing blood serum from participants in completed and ongoing booster studies to look for neutralizing activity against the Omicron variant. In addition, the Company is pursuing an Omicron-specific variant vaccine and will progress it as neede...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
Asian J Surg. 2021 Nov 25:S1015-9584(21)00730-2. doi: 10.1016/j.asjsur.2021.11.032. Online ahead of print.ABSTRACTBACKGROUND: This prospective randomized controlled study compared the short- and long-term efficacy and advantages of modified Park's submucosal over Milligan-Morgan hemorrhoidectomy (MMH) in the treatment of grade III and IV circumferential prolapsed hemorrhoids (CPH).METHODS: A total of 186 consecutive patients with grade III or IV CPH were enrolled. The patients were randomized to MPSH (n = 93) or MMH (n = 93) treatment groups. Patient data included demographics, clinical characteristics, surgical parameters...
Source: Asian Journal of Surgery - Category: Surgery Authors: Source Type: research
Med Sci Monit. 2021 Nov 29;27:e934436. doi: 10.12659/MSM.934436.ABSTRACTBACKGROUND The main cause of death in patients with hepatocellular carcinoma (HCC) with portal hypertension is esophageal and gastric variceal bleeding caused by severe portal hypertension; therefore, the treatment of portal hypertension is particularly important to prolong the survival of patients. The therapeutic efficacy and safety of transarterial chemoembolization (TACE) combined with a transjugular intrahepatic portosystemic shunt (TIPS) for HCC with esophageal and gastric variceal bleeding has been rarely reported. The aim of this study was to a...
Source: Medical Science Monitor - Category: Research Authors: Source Type: research
Am Surg. 2021 Nov 29:31348211048835. doi: 10.1177/00031348211048835. Online ahead of print.ABSTRACTMajor injury of the innominate artery is traditionally treated with an open repair which is technically challenging, associated with large volumes of blood loss and prolonged operative times. Endovascular treatment with covered stent placement across the injury is an attractive alternative. However, placement of a single covered stent across the innominate artery bifurcation into one of its distal branches will not prevent bleeding because of retrograde perfusion from the unstented branch distal to the bifurcation. Here, we r...
Source: The American Surgeon - Category: Surgery Authors: Source Type: research
Am Surg. 2021 Nov 29:31348211054069. doi: 10.1177/00031348211054069. Online ahead of print.NO ABSTRACTPMID:34841911 | DOI:10.1177/00031348211054069
Source: The American Surgeon - Category: Surgery Authors: Source Type: research
Conclusion: in an unselected cohort, LAAC with the systematic use of CPD was a feasible, safe and effective therapeutic option for LAAT both acutely and after long-term follow-up.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research
Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with the Bruton’s tyrosine kinase (Btk) inhibitor, ibrutinib. Btk and related kinases (like Tec) are expressed in non-leukemic hematopoietic cells and can be targeted by ibrutinib. In platelets, ibrutinib therapy is associated with bleeding complications mostly due to off-target effects. But the ability of platelets to respond to bacteria in CLL, and the potential impact of ibrutinib on platelet innate immune functions remain unknown. FcγRIIA is a tyrosine kin...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
The choice of antithrombotic therapy for patients undergoing intervention for peripheral arterial diseases is complex, with different antithrombotics appearing to be the best option for different patient groups.1 The COMPASS and VOYAGER trials aimed to simplify these decisions.2,3 While COMPASS examined patients with stable peripheral arterial disease, VOYAGER examined patients undergoing intervention. The headline findings were similar in that “dual pathway inhibition” with aspirin and low dose rivaroxaban reduced the primary endpoint (a composite of limb and cardiovascular events), at the cost of increased major bleeding events.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research
AbstractPurposeRobot-assisted pelvic screw fixation is a new technology with promising benefits on intraoperative outcomes for patients with posterior pelvic ring injuries. We aim to compare robot-assisted pelvic screw fixation to the traditional fluoroscopy-assisted technique with regards to intraoperative and postoperative outcomes.MethodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used along with a search of electronic information to identify all studies comparing the outcomes of robot-assisted versus conventional screw fixation in patients with posterior pelvic ring i...
Source: European Journal of Orthopaedic Surgery and Traumatology - Category: Orthopaedics Source Type: research
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