Response prediction of neoadjuvant chemoradiation therapy in locally advanced rectal cancer using CT-based fractal dimension analysis

ConclusionFD on pretreatment CT is a promising parameter for predicting pCR to nCRT in patients with LARC and could be used to help make treatment decisions.Key Points•Fractal dimension analysis on pretreatment CT was associated with response to neo-adjuvant chemoradiation in patients with locally advanced rectal cancer.•Fractal dimension is a promising biomarker for predicting pCR to nCRT and may potentially select patients for individualized therapy.

http://link.springer.com/10.1007/s00330-021-08303-z

Source: European Radiology - October 13, 2021 Category: Radiology Source Type: research