Factors predicting the risk of biochemical incomplete response in well-differentiated thyroid cancer after total thyroidectomy

Background Differentiated thyroid cancer (DTC) is the most common endocrine carcinoma with an overall good prognosis. However, persistent or recurrent disease (P/R disease) and incomplete biochemical response (BIR) are causes of morbidity. Histopathology and TNM stage may not predict P/R disease and BIR in all patients. Various clinical parameters, histopathological features and preablative-stimulated thyroglobulin (presTg) have been proposed to predicts P/R disease. However, there is uncertainty for presTg cutoff and diagnostic accuracy. The study’s objective was to predict the BIR before radioiodine ablation from available clinical, histopathological and biochemical parameters. Methods A retrospective, single-center study, including DTC patients, was done. Demography and factors predicting BIR evaluated. Result In comparison to the patients in remission, patients with BIR were older (P = 0.042), had higher presTg (P
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research