Self-reported Wheat Sensitivity in Irritable Bowel Syndrome and Healthy Subjects: Prevalence of Celiac Markers and Response to Wheat-free Diet

CONCLUSIONS: Eleven percent of patients with IBS self-reported wheat sensitivity. None of them had positive celiac serology; 60.9% were positive for HLA DQ2 and DQ8, suggesting a possible genetic basis. All of them improved symptomatically on a wheat-free diet.PMID:34642280 | DOI:10.5056/jnm20086
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Authors: Source Type: research