Abnormal Functional Brain Network in Parkinson's Disease and the Effect of Acute Deep Brain Stimulation

Conclusion: Compared with HC, patients with PD showed the following characteristics: slowed EEG background activity, decreased clustering coefficient and local efficiency of the brain network, as well as both increased and decreased functional connectivity between different brain areas. Acute DBS induces a local response of the brain network in patients with PD, mainly showing decreased functional connectivity in a few brain regions in the beta2 frequency band.
Source: Frontiers in Neurology - Category: Neurology Source Type: research