miRNA-34b/c regulates mucus secretion in RSV-infected airway epithelial cells by targeting FGFR1

This study identified that miR-34b/miR-34c was involved in c-Jun-regulated MUC5AC production by targeting FGFR1 in RSV-infected airway epithelial cells. These results provide some useful insights into the molecular mechanisms of mucus hypersecretion which may also bring new potential strategies to improve mucus hypersecretion in RSV disease.PMID:34636482 | DOI:10.1111/jcmm.16988

Source: J Cell Mol Med - October 12, 2021 Category: Molecular Biology Authors: Wenkai Li Xizi Du Yu Yang Lin Yuan Ming Yang Ling Qin Leyuan Wang Kai Zhou Yang Xiang Xiangping Qu Huijun Liu Xiaoqun Qin Gelei Xiao Chi Liu Source Type: research