Role of fibulin-1 gene promoter methylation in the carcinogenesis and development of tongue squamous cell carcinoma

Recently, fibulin-1 (FBLN1) has been shown to be downregulated in various cancers via promoter hypermethylation. Our study aimed to determine the expression and methylation status of FBLN1 in tongue squamous cell carcinoma (TSCC) tissues and cells.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - October 13, 2021 Category: ENT & OMF Authors: Fang Yang, Jing Shi, Liangyu Zhang, Hongyan Wang, Yang Li Source Type: research