The Development of Machine Learning Methods in discriminating Secretory Proteins of Malaria Parasite

Curr Med Chem. 2021 Oct 5. doi: 10.2174/0929867328666211005140625. Online ahead of print.ABSTRACTMalaria caused by Plasmodium falciparum is one of the major infectious diseases in the world. It is essential to exploit an effective method to predict secretory proteins of malaria parasites to develop effective cures and treatment. Biochemical assays can provide details for accurate identification of the secretory proteins, but these methods are expensive and time-consuming. In this paper, we summarized the machine learning-based identification algorithms and compared the construction strategies between different computational methods. Also, we discussed the use of machine learning to improve the ability of algorithms to identify proteins secreted by malaria parasites.PMID:34636289 | DOI:10.2174/0929867328666211005140625
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Source Type: research