Diagnostic accuracy of in vivo early tumor imaging from probe-based confocal laser endomicroscopy versus histologic examination in head and neck squamous cell carcinoma

ConclusionFinal sensitivity scores were reasonable but final specificity scores were low. pCLE zones used to calculate specificity were acquired in areas of tumor margins, and the poor quality of the images acquired in these areas explains the final low specificity scores.Clinical relevancePractical adjustments and technical training are needed to analyze head and neck lesions in various anatomical sites in real-time by pCLE.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research