Impacts of Diabetes, Aging, and Hearing Loss on Speech-on-Speech Masking and Spatial Release in a Large Veteran Cohort

Conclusions In a large cohort of Veterans, low-frequency hearing loss and older age negatively impact speech understanding. Compared with nondiabetics, individuals with controlled DM2 have additional auditory deficits beyond those associated with hearing loss or aging. These results provide a potential explanation for why individuals who have diabetes and/or are older often report difficulty understanding speech in real-world listening environments. Supplemental Material https://doi.org/10.23641/asha.16746475.PMID:34633838 | DOI:10.1044/2021_AJA-21-00022
Source: American Journal of Audiology - Category: Audiology Authors: Source Type: research

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ConclusionMiR-93-5p, via targeting Sirt1, could affect the vascular permeability and acellular capillaries and mitigate the inflammation and oxidative stress in the retinas, which may play a critical role in DR.
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Conditions:   Type2 Diabetes;   Diabetes Mellitus, Type 2;   Endocrine System Diseases;   Nutritional and Metabolic Diseases;   Glucose Metabolism Disorders (Including Diabetes Mellitus);   Diabetes Mellitus Intervention:   Behavioral: Personal Health Coaching and Diabetes Education in Group Sponsors:   Indonesia University;   Provincial Health Services Authority Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsWithin the limitations of this randomized, controlled trial, physical activity over a period of 6 months is a health-promoting measure for patients with T2DM and improves both periodontal health and HbA1c concentrations.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
Conclusion: Chromosomal microdeletions in 16 p11.2, including the SH2B1 gene, in children are associated with severe, early-onset obesity and comorbidities associated with insulin resistance. Early genetic testing in suspicious patients and early screening for comorbidities is recommended.
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research
Condition:   Diabetes Mellitus, Type 2 Interventions:   Drug: LY3502970;   Drug: Placebo Sponsor:   Eli Lilly and Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsDapagliflozin seems to offer greater value for money than the ARNI for patients with HFrEF and DM. Our results provide support for contemporary guidelines advocating the use of dapagliflozin in these patients.
Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
In conclusion, both SGLT2-i and GLP1-RA seem to have several effects on RAAS, though additional studies are needed to clarify this relationship.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
IJERPH, Vol. 18, Pages 11056: Association between Dietary Habits and Type 2 Diabetes Mellitus in Yangon, Myanmar: A Case–Control Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph182111056 Authors: Satomi Ueno Myo Nyein Aung Motoyuki Yuasa Ahmad Ishtiaq Ei Thinzar Khin Tint Swe Latt Saiyud Moolphate Setsuko Sato Takeshi Tanigawa In Myanmar, the escalating prevalence of type 2 diabetes mellitus (T2DM) and impaired glucose tolerance among adults was recently reported, with the highest prevalence in the Yangon Region. The aim of the present study was to id...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
This study aims to determine the prevalence of cognitive impairment and its associated risk factors among the elderly patients having type 2 diabetes mellitus (T2DM) in Hospital Kuala Lumpur, Malaysia. This is a cross-sectional study involving 113 participants who were attending the physician clinic. The participants were selected using the universal sampling method. The tools included a sociodemographic questionnaire, the Montreal Cognitive Assessment, the Depression Anxiety Stress Scale, and the Mini-International Neuropsychiatry Interview. Descriptive analysis was performed and followed by multiple logistic regression. ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Diabetes mellitus and thyroid disease are two areas of broad interest in the field of endocrinology and metabolism. Variation of thyroid hormone concentration, even within the normal range, may portend the ons...
Source: BMC Medicine - Category: Internal Medicine Authors: Tags: Research article Source Type: research
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