Does neoadjuvant chemotherapy diminish the sex disparity in bladder cancer survival after radical cystectomy?

CONCLUSIONS: In a contemporary cohort of subjects who underwent RC, administration of NAC narrows the sex survival-gap in advanced stage bladder cancer. Strategies to improve NAC usage in women should be adopted to overcome potential sex-specific differences such as delayed diagnosis, anatomic differences in higher stage disease, or altered tumor biology which may contribute to differences in oncologic outcomes.PMID:34629282 | DOI:10.1016/j.urolonc.2021.09.003

Source: Urologic Oncology - October 11, 2021 Category: Urology & Nephrology Authors: Siv Venkat Aleem I Khan Benjamin L Taylor Neal A Patel Bashir Al Hussein Al Awamlh Lina Posada Calderon Jonathan Fainberg Jonathan Shoag Douglas S Scherr Source Type: research