Insights from tissue “omics” analysis on intestinal remodeling in celiac disease

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Source: Proteomics - Category: Biochemistry Authors: Tags: Research Article Source Type: research

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CONCLUSIONS: This is the first case report describing delayed seropositivity of CD and suggests that CD enteropathy may precede positive serology and could cause severe glucose dysregulation in patients with T1DM.PMID:34859874 | DOI:10.26355/eurrev_202111_27262
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Source Type: research
Celiac disease does not pose an increased risk for COVID-19-related hospitalization and death, according to the largest study to date to look at COVID-19 outcomes in this patient population.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Conclusions Follow-up of coeliac disease patients is suboptimal in Central Europe. Many patients are not followed regularly. A lot of patients are not referred to a dietitian. The recommendations on the optimal follow-up of coeliac disease patients are needed in order to improve patient care.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original articles: Gastroenterology Source Type: research
Conclusion Overall, with minor modifications, the Hebrew version of the CDDUX was found to be a valid measure of children’s celiac-related quality of life when measured across children’s self-reports and parent-proxy reports. The CDDUX provides meaningful measurement and allows child–parent comparison.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original articles: Gastroenterology Source Type: research
We describe the histological findings of coeliac and Crohn's disease, gastrointestinal food allergic diseases, Langerhans cell histiocytosis, nutritional deficiencies and infections. Finally, we suggest the principal issues in the drafting the pathological report for appropriate interpretation and usefulness in clinical practice.PMID:34856605 | DOI:10.32074/1591-951X-338
Source: Pathologica - Category: Pathology Authors: Source Type: research
Do individuals with autoimmune hepatitis demonstrate a higher prevalence of celiac disease compared to the general population?Liver International
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Celiac disease (CD) is an immune-mediated enteropathy that arises in genetically susceptible individuals carrying the human leucocyte antigen (HLA) DQ2 or DQ8 haplotypes. It is characterized, histologically, by an increased number of intraepithelial T lymphocyte (> 25/100 epithelial cells) with or without crypt hyperplasia, and variable villous atrophy. These histological features are not pathognomonic of CD and integration with clinical, genetical and serological data is required to diagnose CD.   High serum levels of IgA anti-tissue transglutaminase type 2 (anti-TG2) and anti-endomysium (EMA) are typical features of untreated CD.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Commentary Source Type: research
CONCLUSION: The frequency of temporary elevated anti-tissue transglutaminase levels is considered high. Our study confirms the recommendation that in the case of moderate anti-tissue transglutaminase levels with lack of clinical symptoms, control antibody measurement is necessary with ongoing gluten consumption. Orv Hetil. 2021; 162(48): 1924-1930.PMID:34839274 | DOI:10.1556/650.2021.32287
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
CONCLUSION: The frequency of temporary elevated anti-tissue transglutaminase levels is considered high. Our study confirms the recommendation that in the case of moderate anti-tissue transglutaminase levels with lack of clinical symptoms, control antibody measurement is necessary with ongoing gluten consumption. Orv Hetil. 2021; 162(48): 1924-1930.PMID:34839274 | DOI:10.1556/650.2021.32287
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
CONCLUSION: The frequency of temporary elevated anti-tissue transglutaminase levels is considered high. Our study confirms the recommendation that in the case of moderate anti-tissue transglutaminase levels with lack of clinical symptoms, control antibody measurement is necessary with ongoing gluten consumption. Orv Hetil. 2021; 162(48): 1924-1930.PMID:34839274 | DOI:10.1556/650.2021.32287
Source: Orvosi Hetilap - Category: General Medicine Authors: Source Type: research
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