Study: Triptans give best pain relief for migraines, but have more side effects than newer drugs

A class of drugs called triptans remains the most effective treatment for migraines, an analysis of data from more than 60 studies published Monday by JAMA Network Open found.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Since the emergence of the COVID-19 pandemic, Johnson &Johnson (the Company) has been closely monitoring newly emerging COVID-19 variants. In collaboration with academic groups in South Africa and around the world, the Company has been evaluating the effectiveness of its COVID-19 vaccine across variants, including now the new and rapidly spreading Omicron variant. The Company is testing blood serum from participants in completed and ongoing booster studies to look for neutralizing activity against the Omicron variant. In addition, the Company is pursuing an Omicron-specific variant vaccine and will progress it as neede...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
CONCLUSIONS: Our study found that diagnostic criteria and acute treatment of migraine were well known by the majority of general practitioners, in contrast of preventive treatment.PMID:34840637 | PMC:PMC8616706 | DOI:10.1155/2021/9327363
Source: Pain Research and Management - Category: Anesthesiology Authors: Source Type: research
Headache. 2021 Nov 28. doi: 10.1111/head.14237. Online ahead of print.ABSTRACTOBJECTIVE: To validate the diagnoses and to investigate epidemiological data from an international, non-clinic-based, and large (n = 1604) survey of participants with cluster headache.BACKGROUND: There are several limitations in current epidemiological data in cluster headache including a lack of large non-clinic-based studies. There is also limited information on several aspects of cluster headache, such as pediatric incidence.METHODS: The International Cluster Headache Questionnaire was an internet-based survey that included questions on cluste...
Source: Headache - Category: Neurology Authors: Source Type: research
Discussion With COVID-19, the scientific research process is playing out daily in the press where the general public can see for themselves and share in the new knowledge and frustrating events that occur usually behind the curtain of science. People try to understand the little snippets of new knowledge that come forth and how they fit into the COVID problem, and most importantly how it may affect themselves, the people they care about and their community. Patients and families daily ask questions of their health care providers who themselves have the same questions, and answer something like “We’re learning s...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
CONCLUSIONS: We presented a rare case of orbital metastasis from ampullary adenocarcinoma. This should be considered in the differential diagnosis of patients with a history of ampullary adenocarcinoma who present with symptoms referring to the relevant locations.PMID:34833456 | PMC:PMC8624159 | DOI:10.3390/medicina57111238
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Source Type: research
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
ConclusionsBoth anodal and cathodal tDCS are promising for migraine prevention. However, there is a need for larger and rigorous RCTs and standardized procedures. Additionally, the potential benefits and targeted neurostimulation protocols should be assessed for specific subgroups of patients.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
DiscussionResults of this trial will help to clarify the value of auricular acupressure therapy in preventing and relieving overall and certain adverse events following immunization after injection of COVID-19 vaccine.Trial registrationChina Clinical Trial Registry (ChiCTR) (ChiCTR2100043210). Registered on 8 February, 2021.
Source: Trials - Category: Research Source Type: clinical trials
Lancet Infect Dis. 2021 Nov 23:S1473-3099(21)00677-0. doi: 10.1016/S1473-3099(21)00677-0. Online ahead of print.ABSTRACTBACKGROUND: Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate.METHODS: HERALD is a randomised, observer-blinded, placebo-controlled, phase 2b/3 clinical trial conducted in 47 centres in ten countries in Europe and Latin America. By use of an interactive web response system and stratification by country and age group (18-60 years and ≥61 years), adults with no history of virolo...
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
CONCLUSIONS: Intranasal ketorolac was non-inferior to intravenous ketorolac for reducing migraine headache pain in the emergency department.PMID:34822214 | DOI:10.1111/acem.14422
Source: Accident and Emergency Nursing - Category: Emergency Medicine Authors: Source Type: research
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