The missing X factor in Alzheimer disease

Nature Reviews Neurology, Published online: 11 October 2021; doi:10.1038/s41582-021-00573-xTwo-thirds of patients with Alzheimer disease (AD) are women, and sex differences in AD pathology have been observed, yet little is known about the role of sex chromosomes in AD. New research suggests that X-linked gene expression modifies AD risk in a sex-specific manner. This knowledge could aid the development of precision medicine approaches for AD.
Source: Nature Reviews Neurology - Category: Neurology Authors: Source Type: research