Moment-to-moment brain signal variability reliably predicts psychiatric treatment outcome

Biomarkers of psychiatric treatment response remain elusive. Functional magnetic resonance imaging (fMRI) has shown promise, but low reliability has limited the utility of typical fMRI measures (e.g., average brain signal) as harbingers of treatment success. Notably, although historically considered a source of “noise,” temporal brain signal variability continues to gain momentum as a sensitive and reliable indicator of individual differences in neural efficacy, yet has not been examined in relation to psychiatric treatment outcomes.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Archival Report Source Type: research