Circulating tumor DNA in stage III colorectal cancer, beyond minimal residual disease detection, towards assessment of adjuvant therapy efficacy and clinical behavior of recurrences

CONCLUSIONS: Serial postoperative ctDNA analysis has a strong prognostic value and enables tumor growth rate assessment. The novel combination of ctDNA detection and growth rate assessment provides unique opportunities for guiding decision-making.PMID:34625408 | DOI:10.1158/1078-0432.CCR-21-2404

Source: Clinical Cancer Research - October 9, 2021 Category: Cancer & Oncology Authors: Tenna Vesterman Henriksen Noelia Tarazona Amanda Frydendahl Thomas Reinert Francisco Gimeno-Valiente Juan Antonio Carbonell-Asins Shruti Sharma Derrick Renner Dina Hafez Desamparados Roda Marisol Huerta Susana Rosell ó Anders Husted Madsen Uffe S L øve Source Type: research