< em > Spirulina platensis < /em > and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis model

In this study, we pursued the effect of biopterin glucoside, another bioactive ingredient of Spirulina (Arthrospira) platensis. We found Spirulina (Arthrospira) platensis and biopterin glucoside oral administrations effectively alleviated oxidative stress, inflammation and insulin signal failure, and prevented fibroblast growth factor 21 gene overexpression in non-alcoholic steatohepatitis rat livers. We concluded biopterin glucoside is a major component of Spirulina (Arthrospira) platensis action.PMID:34616107 | PMC:PMC8482380 | DOI:10.3164/jcbn.20-201

Source: Clinical Biochemistry - October 7, 2021 Category: Biochemistry Authors: Yuri Fujihara Yasumasa Kodo Shin-Ichi Miyoshi Ritsuko Watanabe Hiroshi Toyoda Mitsumasa Mankura Hideaki Kabuto Fusako Takayama Source Type: research