The urokinase plasminogen activator receptor (uPAR) controls macrophage phagocytosis in intestinal inflammation

Conclusions
These findings point to uPAR as an essential component of intestinal macrophage functions and unravel a new potential target to control mucosal inflammation in IBD.

Source: Gut - March 6, 2015 Category: Gastroenterology Authors: Genua, M., D'Alessio, S., Cibella, J., Gandelli, A., Sala, E., Correale, C., Spinelli, A., Arena, V., Malesci, A., Rutella, S., Ploplis, V. A., Vetrano, S., Danese, S. Tags: Crohn's disease Inflammatory bowel disease Source Type: research