Stem cells treatment for wilson disease

Curr Stem Cell Res Ther. 2021 Oct 6. doi: 10.2174/1574888X16666211006111556. Online ahead of print.ABSTRACTWilson disease (WD) is a copper excretion disorder, mainly caused by mutations in the ATP7B gene. Pharmacological therapies and liver transplantation are currently the main treatment methods for WD, but they face problems such as drug treatment compliance, adverse reactions, and shortage of liver donors. Stem cell therapy of WD may correct abnormal copper metabolism permanently, which is the focus of current research. In this review, we summarized the latest research on stem cells treatment for WD, as well as current challenges and future expectations.PMID:34615454 | DOI:10.2174/1574888X16666211006111556
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Source Type: research