Acupuncture therapy for Alzheimer's disease: The effectiveness and potential mechanisms

This study may help to understand the theoretical basis and potential molecular mechanisms of acupuncture therapy for AD.PMID:34623030 | DOI:10.1002/ar.24780
Source: Anatomical Record - Category: Anatomy Authors: Source Type: research

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The researchers studied samples of brain tissue from people with and without Alzheimer's disease.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia subscribers-only Source Type: blogs
This article discussed the pathophysiology of dementia, as well as a list of herbal medications that can easily cross the BBB and have a therapeutic effect on dementia.PMID:35031512 | DOI:10.1016/j.arr.2022.101560
Source: Ageing Research Reviews - Category: Genetics & Stem Cells Authors: Source Type: research
AbstractPurposeTo compare two artificial intelligence software packages performing normative brain volumetry and explore whether they could differently impact dementia diagnostics in a clinical context.MethodsSixty patients (20 Alzheimer ’s disease, 20 frontotemporal dementia, 20 mild cognitive impairment) and 20 controls were included retrospectively. One MRI per subject was processed by software packages from two proprietary manufacturers, producing two quantitative reports per subject. Two neuroradiologists assigned forced-choi ce diagnoses using only the normative volumetry data in these reports. They classified ...
Source: Neuroradiology - Category: Radiology Source Type: research
Alzheimers Res Ther. 2022 Jan 13;14(1):9. doi: 10.1186/s13195-021-00955-9.ABSTRACTBACKGROUND: Lipocalin-2 is a glycoprotein that is involved in various physiological and pathophysiological processes. In the brain, it is expressed in response to vascular and other brain injury, as well as in Alzheimer's disease in reactive microglia and astrocytes. Plasma Lipocalin-2 has been proposed as a biomarker for Alzheimer's disease but available data is scarce and inconsistent. Thus, we evaluated plasma Lipocalin-2 in the context of Alzheimer's disease, differential diagnoses, other biomarkers, and clinical data.METHODS: For this tw...
Source: Cell Research - Category: Cytology Authors: Source Type: research
CONCLUSION: dCA efficiency was reduced in task-activation in healthy but not cognitively impaired participants. These results indicate differences in neurovascular processing in healthy older adults relative to cognitively impaired individuals.PMID:35026972 | DOI:10.2174/1567205019666211227102936
Source: Current Alzheimer Research - Category: Neurology Authors: Source Type: research
HUMANITY is locked in a vicious battle with dementia and the fight is set to intensify in the coming decades as populations age. Research aims to shed light on the early risk factors in a bid to forestall brain decline. New research published today shows a condition affecting 2.3 million in the UK directly causes Alzheimer's - the most common cause of dementia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CNS Neurol Disord Drug Targets. 2022 Jan 11. doi: 10.2174/1871527321666220111124928. Online ahead of print.ABSTRACTThe new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) represents a public health problem worldwide. COVID-19 triggers a maladaptive cytokine release commonly referred to as cytokine storm syndrome with increased production of pro-inflammatory cytokines, which also appears to contribute to chronic neuro-inflammation and neurodegenerative disorders' appearance, including multiple sclerosis, Parkinson's disease, and Alzheimer's disease. In this context, SARS-CoV-2 might enter the...
Source: CNS and Neurological Disorders Drug Targets - Category: Drugs & Pharmacology Authors: Source Type: research
DISCUSSION: These recommendations are a first step for clinicians to address brain health with patients and potentially help them prevent cognitive decline. To ensure there is routine care for brain health, proper incentives and policies must be instituted and more education for consumers should be provided.PMID:35026040 | DOI:10.1002/alz.12535
Source: The Journal of Alzheimers Association - Category: Psychiatry Authors: Source Type: research
DISCUSSION: Neurodegenerative biomarkers were elevated to levels observed in AD dementia and associated with encephalopathy and worse outcomes among hospitalized COVID-19 patients.PMID:35023610 | DOI:10.1002/alz.12556
Source: The Journal of Alzheimers Association - Category: Psychiatry Authors: Source Type: research
Conclusions: The majority of researches seem to converge to the aspect that the physical activity offers considerable benefits to the people suffering from the Alzheimer's disease or any other kind of dementia. More specifically, it contributes to the stability and the improvement of mental function as well as to the delay of the appearance of serious neuropsychiatric symptoms such as depression, confusion, and apathy. Moreover, the role of physical activity is significant in the improvement of functional ability of patients suffering from dementia resulting in the enforcement of autonomy in everyday activities and the con...
Source: Adv Data - Category: Epidemiology Authors: Source Type: research
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