The Effects of Dexmedetomidine on Anesthetic Outcomes following Maxillomandibular Advancement Surgery

Research supports that maxillomandibular advancement (MMA) surgery is an effective treatment modality for severe obstructive sleep apnea (OSA). In a systematic review, Ankichetty, et al, found that the use of alpha 2 agonists in OSA patients reduces the requirement of perioperative analgesics, but no randomized clinical trials with the use of dexmedetomidine (DEX) in OSA patients exist.1 Furthermore, while there are several studies evaluating peri-operative parameters in patients who have undergone Stanford Protocol's Phase I OSA surgeries, published studies regarding the usage of intra-operative DEX and anesthetic outcomes following MMA surgery are difficult to find.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research