Dynamic Network Connectivity Reveals Markers of Response to Deep Brain Stimulation in Parkinson ’s Disease

Conclusion: Given the widespread effects of dopamine depletion in PD, analysis of whole brain networks is critical to our understanding of the pathophysiology of this disease. Only by leveraging graph theoretical analysis of dynamic FC were we able to isolate a hypoconnected brain state that contained distinct network properties associated with the clinical effects of STN-DBS.
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research