Dairy products and the risk of developing prostate cancer: A large ‐scale cohort study (JACC Study) in Japan

This study investigates the association between consumption of dairy product and development of prostate cancer using a large-scale cohort study in Japan. Our study makes a significant contribution to the literature because we were able to show statistically significant associations and dose –response relationships between high intake of milk and yogurt and prostate cancer, even after adjusting for potential confounders including body mass index and total energy intake. AbstractDairy products have been indicated as a risk factor for prostate cancer. However, only a few epidemiological studies have reported dairy products as being a risk factor for prostate cancer in Japan, reporting contradictory results. We therefore investigated the association between the intake of dairy products and the occurrence of prostate cancer through a large-scale cohort study. The Japan Collaborative Cohort study analyzed approximately 110,000 residents from various Japanese districts who participated in our questionnaire survey during 1988 –1990. The subjects of the present study were 26,464 men (age range: 40–79 years) from 24 districts wherein cancer incidence was reported. Their clinical course was followed up until 2009. Hazard ratios (HRs) were calculated using Cox's proportional hazards model, adjusted for age, survey area, family history of prostate cancer, body mass index, and total energy intake. For diet, we calculated the HRs associated with intermediate and high consumption of ...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: RESEARCH ARTICLE Source Type: research