Transcranial Magnetic Resonance-Guided Histotripsy for Brain Surgery: Pre-clinical Investigation

Histotripsy has been previously applied to target various cranial locations in vitro through an excised human skull. Recently, a transcranial magnetic resonance (MR)-guided histotripsy (tcMRgHt) system was developed, enabling pre-clinical investigations of tcMRgHt for brain surgery. To determine the feasibility of in vivo transcranial histotripsy, tcMRgHt treatment was delivered to eight pigs using a 700-kHz, 128-element, MR-compatible phased-array transducer inside a 3-T magnetic resonance imaging (MRI) scanner.

Source: Ultrasound in Medicine and Biology - October 4, 2021 Category: Radiology Authors: Ning Lu, Dinank Gupta, Badih J. Daou, Adam Fox, Dave Choi, Jonathan R. Sukovich, Timothy L. Hall, Sandra Camelo-Piragua, Neeraj Chaudhary, John Snell, Aditya S. Pandey, Douglas C. Noll, Zhen Xu Tags: Original Contribution Source Type: research