Validation of Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium (U19)

Funding Opportunity Number: RFA-AR-15-014 Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCFDA Number: 93.846Eligible Applicants State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationPrivate institutions of higher educationFor profit organizations other than small businessesSmall businessesOthers (see text field entitled "Additional Information on Eligibility" for clarification)Agency Name: HHS-NIH11Closing Date: Jun 01, 2015Award Ceiling: Expected Number of Awards: 4Creation Date: Mar 06, 2015Funding Opportunity Description: The purpose of this FOA is to solicit applications for the Validation of Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium. The NIAMS, on behalf of the National Institutes of Health, intends to capitalize on recent advances in the science of Patient Reported Outcomes (PROs) to measure the patient experience in clinical care a...
Source: Grants.gov - Category: Research Tags: Health Source Type: funding

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AbstractTo evaluate the efficacy of selective retina therapy (SRT) in patients with diabetic macular edema (DME) based on pretreatment central foveal thickness (CFT). Seventy-two eyes of 63 patients with DME who had previously undergone SRT were included. Patients were divided into two groups based on the CFT at baseline. Group 1 was composed of 35 eyes with CFT  
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Authors: Furaz Czerpak K, Gruss Vergara E, Barril Cuadrado G, Pérez Fernández E, Benavides N, de la Flor J, Mendez Á, Martín R Abstract INTRODUCTION: Hypertension is very common in haemodialysis (HD) patients, and is associated with increased morbidity and mortality rates. The goals of our research were to: 1. Measure blood pressure (BP) during HD sessions; 2. Study BP in between HD sessions with 44-hour Ambulatory Blood Pressure Monitoring (ABPM); 3. Identify differences between the BP recorded during HD and with the ABPM; 4. Evaluate changes in treatment after the ABPM; 5. Perform bioi...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
Pathologic lymphatic remodeling in lymphedema evolves during periods of tissue inflammation and hypoxia through poorly defined processes. In human and mouse lymphedema, there is a significant increase of hypoxia inducible factor 1 α (HIF-1α), but a reduction of HIF-2α protein expression in lymphatic endothelial cells (LECs). We questioned whether dysregulated expression of these transcription factors contributes to disease pathogenesis and found that LEC-specific deletion of Hif2α exacerbated lymphedema pathology. Even without lymphatic vascular injury, the loss of LEC-specific Hif2α caused an...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
This study has the potential to transform the diagnosis and treatment of allergic disorders.
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
(Medical College of Georgia at Augusta University) The kidneys often become bulky and dysfunctional in diabetes, and now scientists have found that one path to this damage dramatically reduces the kidney's ability to clean up after itself.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
(Pennington Biomedical Research Center) More than 18 percent of US adults do not know whether they will have enough to eat from day to day, and the numbers are worse for Hispanics, Blacks, people with obesity, and women, a new report shows.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Patellar instability and associated patellar dislocation can result in significant pain, disability, and associated injuries in young athletes. The patellofemoral joint is a complex articulation with stabilizing restraints, both medially and laterally, tha...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Abstract A 67-year-old male diabetic patient with systemic arterial hypertension was admitted to the emergency department with a necrotic ulcer in the left external malleolus and no palpable popliteal or pedal pulses. Arterial Duplex ultrasound identified femoropopliteal occlusion, with popliteal refilling below the knee and a patent peroneal artery. An endovascular procedure was performed, requiring retrograde access to the popliteal artery to re-establish blood flow and deploy a popliteal stent. Technical success was achieved and the patient underwent debridement of the wound. Two days later, about 48 hours after the ope...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
Conclusion: The average cost for complete healing of a sickle cell ulcer with an average area of 14.95 cm2 was R$ 1,288.06.Resumen Objetivo: Identificar los costos desembolsados con el tratamiento de la úlcera de pierna consecuente de la enfermedad de células falciformes bajo la perspectiva del Sistema Único de Salud. Método: Estudio observacional, descriptivo, de evaluación económica del costo-efectividad, llevado a cabo en un centro único, con pacientes portadores de úlcera. Los datos r ecogidos fueron extraídos de la ficha del participante y registrados en f...
Source: Revista da Escola de Enfermagem da USP - Category: Nursing Source Type: research
CONCLUSION We concluded that the pathological effect of treatment with favipiravir on the hematologic system was the suppression in the erythrocyte series, and there were no adverse effects in other hematologic parameters.RESUMO INTRODU ÇÃO Este estudo tem como objetivo avaliar as alterações nos parâmetros hematológicos após o acompanhamento de pacientes que receberam tratamento com favipiravir devido à infecção por Covid-19. MÉTODOS Sessenta e dois casos em tratamento com favipiravir por pelo menos cinco dias devido à infecção...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
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