C/EBP β is a key transcription factor of ox-LDL inducing THP-1 cells to release multiple pro-inflammatory cytokines

ConclusionOur results suggest that ox-LDL stimulation enhances C/EBP β-regulated transcription in THP-1 and C/EBPβ upregulate the release of multiple pro-inflammatory cytokines including IL-18, IL-1β, and IL-6 through direct binding to genes.
Source: Inflammation Research - Category: Research Source Type: research