Parasite protein pirates host cytoskeletal modulator during invasion

Trends Parasitol. 2021 Sep 28:S1471-4922(21)00229-4. doi: 10.1016/j.pt.2021.09.004. Online ahead of print.ABSTRACTHost cytoskeletal rearrangements are an essential yet poorly understood component of Cryptosporidium invasion. Guérin et al. demonstrate that actin rearrangements occur immediately during adherence and capture a unique mechanism of invasion using live-cell imaging. The authors identify a parasite-secreted effector, ROP1, recruited by a host protein, LMO7, involved in pathogenesis.PMID:34598896 | DOI:10.1016/j.pt.2021.09.004
Source: Trends in Parasitology - Category: Parasitology Authors: Source Type: research