Effect of Different Modes of Administration of Dexmedetomidine Combined with Nerve Block on Postoperative Analgesia in Total Knee Arthroplasty

ConclusionsPerineural administration of DEX can significantly prolong the interval until patients report pain for the first time after TKA, relieve postoperative pain, reduce postoperative opioid dosage, and improve postoperative sleep quality and satisfaction with pain control.Trial RegistrationThe trial was registered at the Chinese Clinical Trial Registry, identifier ChiCTR1900025808.
Source: Pain and Therapy - Category: Anesthesiology Source Type: research