SEC61G overexpression and DNA amplification correlates with prognosis and immune cell infiltration in head and neck squamous cell carcinoma

ConclusionsSEC61G is overexpressed in HNSCC and is an independent prognostic factor for OS. SEC61G DNA amplification contributes to overexpression and poor outcome. Interestingly, SEC61G correlates with immune cell infiltration in HNSCC. These findings suggest that SEC61G is a potential broad-spectrum biomarker for prognosis in HNSCC.

Source: Cancer Medicine - September 30, 2021 Category: Cancer & Oncology Authors: Tianzhu Lu, Yiping Chen, Xiaochang Gong, Qiaojuan Guo, Canyang Lin, Qingfeng Luo, Ziwei Tu, Jianji Pan, Jingao Li Tags: RESEARCH ARTICLE Source Type: research