Influence of FPGS, ABCC4, SLC29A1, and MTHFR genes on the pharmacogenomics of fluoropyrimidines in patients with gastrointestinal cancer from the Brazilian Amazon

ConclusionFour polymorphisms of theABCC4,FPGS,SLC29A1, andMTHFR genes are likely to be potential predictive biomarkers for precision medicine in fluoropyrimidine-based treatments in the population of the Brazilian Amazon, which is constituted by a unique genetic background.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research