Altered Lipid Profile Is a Risk Factor for the Poor Progression of COVID-19: From Two Retrospective Cohorts

ConclusionsThe baseline dyslipidemia should be considered as a risk factor for poor prognosis of COVID-19. However, lipid levels may be altered during the COVID-19 course, since lipidology may be distinctly affected by both inflammation and organic damage for SARS-CoV-2.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research

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CONCLUSION: A living COVID-19 registry represents a mechanism to facilitate optimal sharing of data between providers, consumers, health information networks, and health plans through technology-enabled, secure-access electronic health information. Our approach also involves a diversity of new roles in the field, such as using residents, staff, and the quality department, in addition to professional data extractors and the health informatics team.Initially, due to the overwhelming number of infections that continues to accelerate, and the labor/time intense nature of the project, only a small fraction of all patients with ...
Source: Perspectives in Health Information Management - Category: Information Technology Authors: Source Type: research
CONCLUSION: A living COVID-19 registry represents a mechanism to facilitate optimal sharing of data between providers, consumers, health information networks, and health plans through technology-enabled, secure-access electronic health information. Our approach also involves a diversity of new roles in the field, such as using residents, staff, and the quality department, in addition to professional data extractors and the health informatics team.Initially, due to the overwhelming number of infections that continues to accelerate, and the labor/time intense nature of the project, only a small fraction of all patients with ...
Source: Perspectives in Health Information Management - Category: Information Technology Authors: Source Type: research
The global coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus started in March 2020. The conclusions from numerous studies indicate that people with comorbidities, such as arteri...
Source: Lipids in Health and Disease - Category: Lipidology Authors: Tags: Review Source Type: research
CONCLUSIONS: In conclusion, we found that higher total cholesterol and ApoB levels might increase the risk of COVID-19 infection.PMID:34496635 | DOI:10.1161/ATVBAHA.121.316324
Source: Arteriosclerosis, Thrombosis and Vascular Biology - Category: Cardiology Authors: Source Type: research
The current coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory coronavirus  2 (SARS-CoV-2), remains a major public health problem across the globe, despite the availability of vaccines (Hamed et al., 2021). Consequently, there is a continuing need for effective pharmacological therapies that reduce the morbidity and mortality of patients with COVID-19.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
The current coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory coronavirus-2 (SARS-CoV-2), remains a major public health problem across the globe, despite the availability of vaccines (Hamed et al., 2021). In the meantime, we continue to need effective pharmacological therapies that reduce the morbidity and mortality of patients with COVID-19.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Nutr Hosp. 2021 Jun 28. doi: 10.20960/nh.03469. Online ahead of print.ABSTRACTINTRODUCTION: coronavirus disease 2019 (COVID-19) encompasses a wide spectrum of symptoms, including respiratory, gastrointestinal, hematological, and dermatological manifestations. The virus interaction with cells located in the respiratory tract causes the release of inflammatory mediators, whose involvement could be exacerbated by co-existing obesity, diabetes, and cardiovascular events.OBJECTIVES: the objective of this research was to analyze the clinically metabolic status in patients who have suffered COVID-19 disease in order to predict th...
Source: Nutricion Hospitalaria - Category: Nutrition Authors: Source Type: research
Exp Mol Med. 2021 May 25. doi: 10.1038/s12276-021-00624-9. Online ahead of print.ABSTRACTAn ongoing pandemic of coronavirus disease 2019 (COVID-19) is now the greatest threat to global public health. Herbal medicines and their derived natural products have drawn much attention in the treatment of COVID-19, but the detailed mechanisms by which natural products inhibit SARS-CoV-2 have not been elucidated. Here, we show that platycodin D (PD), a triterpenoid saponin abundant in Platycodon grandiflorum (PG), a dietary and medicinal herb commonly used in East Asia, effectively blocks the two main SARS-CoV-2 infection routes via...
Source: Molecular Medicine - Category: Molecular Biology Authors: Source Type: research
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