Commandeering the mammalian Ago2 miRNA network: a newly discovered mechanism of helminth immunomodulation

Trends Parasitol. 2021 Sep 25:S1471-4922(21)00225-7. doi: 10.1016/j.pt.2021.09.001. Online ahead of print.ABSTRACTMicroRNAs (miRNAs) are a class of noncoding RNAs that contribute to a broad range of biological processes through post-transcriptional regulation of gene expression. Helminths exploit this system to target mammalian gene expression, to modulate the host immune response. Recent discoveries have shed new light on the mechanisms involved.PMID:34583903 | DOI:10.1016/j.pt.2021.09.001

Source: Trends in Parasitology - September 29, 2021 Category: Parasitology Authors: Sheila Donnelly Nham Tran Source Type: research