Acute and chronic metabolic effects of carvedilol in high-fructose, high fat diet-fed mice: Implication of β-arrestin2 pathway

In conclusion, carvedilol acutely maintains glucose homeostasis and chronically ameliorates insulin resistance and dyslipidemia in HFrHFD-fed mice. The insulin sensitizing effects of carvedilol are highly correlated with the upregulation of β-arrestin2 pathway.PMID:34570983 | DOI:10.1139/cjpp-2021-0299

Source: Canadian Journal of Physiology and Pharmacology - September 27, 2021 Category: Drugs & Pharmacology Authors: Hoda M S Ahmed Samar G Mohamed Wael S Ibrahim Asmaa M Rezk Amr A A Mahmoud Mona F Mahmoud Islam Ibrahim Source Type: research