Hsa_circ_0088212-mediated miR-520  h/APOA1 axis inhibits osteosarcoma progression

CONCLUSION: Our findings demonstrated that circ_0088212 might exert a tumor-suppressive activity in osteosarcoma by sponging and sequestering miR-520 h away from APOA1. This suggests that the circ_0088212/miR-520 h/APOA1 axis may be a promising therapeutic target for osteosarcoma intervention.PMID:34555726 | DOI:10.1016/j.tranon.2021.101219

Source: Translational Oncology - September 23, 2021 Category: Cancer & Oncology Authors: Feng Liu Xiangyang Zhang Fei Wu Hao Peng Source Type: research