Calcitonin gene related peptide, adrenomedullin and adrenomedullin2 function in uterine artery during human pregnancy

CONCLUSIONS: Relaxation sensitivity of UA for CGRP, ADM and ADM2 is increased during pregnancy via peptide specific involvement of NO system and endothelium derived hyperpolarizing factors, and vascular disruptors such as sFLT-1 and TNFα adversely impact their receptor system in UASMC.PMID:34558598 | DOI:10.1210/endocr/bqab204

Source: Endocrinology - September 24, 2021 Category: Endocrinology Authors: Madhu Chauhan Ancizar Betancourt Meena Balakrishnan Akansha Mishra Jimmy Espinosa Alireza A Shamshirsaz Karin Fox Michael Belfort Chandra Yallampalli Source Type: research