Prevalence of persistent symptoms after treatment for lyme borreliosis: A prospective observational cohort study

Lancet Reg Health Eur. 2021 May 27;6:100142. doi: 10.1016/j.lanepe.2021.100142. eCollection 2021 Jul.ABSTRACTBACKGROUND: Concerns about long-lasting symptoms attributed to Lyme borreliosis (LB) are widespread in the Western world, while such symptoms are highly prevalent in the general population.METHODS: In the largest prospective study to date, adults with physician-confirmed LB were included at the start of antibiotic treatment. Primary outcomes, prevalence of persistent symptoms and symptom severity, were assessed using three-monthly standardised questionnaires during one year. Persistent symptoms were defined as impaired scores for fatigue (CIS, subscale fatigue), cognitive impairment (CFQ) or pain (SF-36, subscale bodily pain) ≥6 months, with onset
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research

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AbstractLyme disease is an infection caused byBorrelia burgdorferi sensu lato, which is transmitted to humans through the bite of an infected Ixodes tick. The majority of patients recover without complications with antibiotic therapy. However, for a minority of patients, accompanying non-specific symptoms can persist for months following completion of therapy. The constellation of symptoms such as fatigue, cognitive dysfunction, and musculoskeletal pain that persist beyond 6  months and are associated with disability have been termed post-treatment Lyme disease syndrome (PTLDS), a subset of a broader term “chron...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Mil Med. 2021 Oct 6:usab420. doi: 10.1093/milmed/usab420. Online ahead of print.ABSTRACTLyme disease is a vector-borne infection that can affect multiple different organ systems. Lyme carditis represents one of these sequelae and is defined by acute onset of high-grade atrioventricular block in the presence of laboratory-confirmed infection. Current guidelines recommend patients with Lyme carditis be admitted for close cardiac monitoring and intravenous antibiotics therapy. Our case illustrates an active duty male who was initially diagnosed with Lyme disease after initially reporting symptoms including headache, fever, ey...
Source: Military Medicine - Category: International Medicine & Public Health Authors: Source Type: research
FINDINGSA UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients. The disease, caused by the tick-borne Borrelia bacterium, generally begins with a bull ’s-eye–shaped rash on the skin, along with fever, headache, chills and muscle pain; if not diagnosed promptly and treated with antibiotics, it can lead to more severe and long-lasting symptoms.UCLA ’s Dr. Dan Ly found that approximately 1 in 3 Black patients who were newly diagnosed with Lyme disease already had related neurological complications such as ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
CONCLUSIONS: Overall, participants desired a more holistic approach to diagnosis, symptom assessment, and symptom management. Recommendations for future research and clinical considerations are discussed.PMID:34582513
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
Conditions:   Post Treatment Lyme Syndrome;   Chronic Pain;   Central Sensitization Interventions:   Drug: Milnacipran with D-cycloserine augmentation;   Drug: Milnacipran with placebo augmentation Sponsor:   Research Foundation for Mental Hygiene, Inc. Terminated
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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