A pharmacological approach assessing the role of mast cells in insulin infusion site inflammation

Conclusion Targeting MC has the potential to extend the longevity of insulin infusion sets by mitigating the inflammatory response. Future studies should be directed at employing other MC models, such as newer Cre/loxP mouse strains, to confirm the sentinel role of MC in insulin infusion therapy.PMID:34561836 | DOI:10.1007/s13346-021-01070-w

Source: Cell Research - September 25, 2021 Category: Cytology Authors: Shereen Kesserwan Li Mao Roshanak Sharafieh Donald L Kreutzer Ulrike Klueh Source Type: research